GeneticsGenesPeer-reviewed
Maternally inherited differences within mitochondrial Complex I control murine healthspan.
Misa Hirose, Paul Schilf, Kim Zarse…·Saleh Mohamed Ibrahim
This study shows that a mutation in mt-Nd2, a mitochondrial complex I gene, reduces lifespan and increases glucose intolerance in mice by affecting tryptophan levels and aging pathways.
13 citations