Author

Qifeng Lyu

Shanghai Jiao Tong UniversityORCID 0000-0002-9885-6522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Yanping KuangiD· 2 shared Aaron J.W. HsuehiD· 1 shared Austin J. CooneyiD· 1 shared Changliang Hou· 1 shared Dali LiiD· 1 shared Fei LiiD· 1 shared Geng G. Tian· 1 shared Haibo WuiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Yanping KuangORCID

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3 papers

Recent·Most cited

Trans-generational maintenance of mitochondrial DNA integrity in oocytes during early folliculogenesis

Qin Xie, Haibo Wu, Jiaxin Qiu, Junbo Liu, Xueyi Jiang, Huihui Wu, Qifeng Lyu, Hui Long, Wenzhi Li, Shuo Zhang, Yuxiao Zhou, Yining Gao, Aaron J.W. Hsueh, Yanping Kuang, Lun Suo

The paper shows that mice reduce pathogenic mtDNA mutations in oocytes during early folliculogenesis, maintaining mitochondrial integrity across generations.

PLoS Genetics · Dec 3, 2025Peer-reviewedGenetics

YTHDF2 is essential for spermatogenesis and fertility through mediating a wave of transcript transition during spermatogonial differentiation

Xinxi Zhao, Zhen Lin, Yong Fan, Yujie Zhang, Fei Li, Tong Hong, Hua Feng, Ming‐Han Tong, Ningling Wang, Yanping Kuang, Qifeng Lyu

This study shows YTHDF2 is essential for mouse spermatogenesis and fertility by regulating transcript transitions during spermatogonial differentiation.

bioRxiv · Apr 30, 2020 · PreprintGenetics

Offspring production of ovarian organoids derived from spermatogonial stem cells by chromatin reorganization

Huacheng Luo, Xiaoyong Li, Geng G. Tian, Dali Li, Changliang Hou, Xinbao Ding, Lin Hou, Qifeng Lyu, Yunze Yang, Austin J. Cooney, Wenhai Xie, Ji Xiong, Hu Wang, Xiaodong Zhao, Ji Wu

The paper demonstrates the production of offspring from oocytes derived from mouse spermatogonial stem cells through chromatin reorganization and identifies key factors involved in germline stem cell conversion.

bioRxiv · Sep 10, 2019 · PreprintGenetics