Offspring production of ovarian organoids derived from spermatogonial stem cells by chromatin reorganization
Huacheng Luo, Xiaoyong Li, Geng G. Tian, Dali Li, Changliang Hou, Xinbao Ding, Lin Hou, Qifeng Lyu, Yunze Yang, Austin J. Cooney, Wenhai Xie, Ji Xiong, Hu Wang, Xiaodong Zhao, Ji Wu
The paper demonstrates the production of offspring from oocytes derived from mouse spermatogonial stem cells through chromatin reorganization and identifies key factors involved in germline stem cell conversion.
bioRxiv · Sep 10, 2019 · PreprintGenetics