Daniel K. Fabian

Expansion of chromosome F heterochromatin in parthenogenetic Drosophila mercatorum

The paper identifies genomic changes in parthenogenetic Drosophila mercatorum, finding a 30-fold expansion of heterochromatin on Muller element F correlates with parthenogenetic ability.

Large-Scale Comparative Transcriptomic Analysis of CHO Cell Functional Adaptation to Recombinant Monoclonal Antibody Production

The paper compares transcriptomic changes in CHO cells producing different recombinant mAbs, finding adaptive mRNA abundance changes linked to mAb production and cellular capacity.

Drosophila Evolution over Space and Time (DEST) - A New Population Genomics Resource

The paper develops a bioinformatics pipeline to integrate Drosophila melanogaster genomic data from diverse sources, creating a large dataset called DEST for population genetics analysis.

Common genetic associations between age-related diseases

This study identifies genetic associations between age-related diseases, finding four clusters with shared age-of-onset profiles and aging-related genes, and suggests drug repurposing for multiple age-dependent diseases.

Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice

This study compares transcriptomic changes in long- and short-lived mouse models of ageing, identifying mitochondrial metabolism as a key factor and showing that progeroid mice exhibit gene expression patterns similar to normal ageing.