Author

Shobhita Gupta

Cornell UniversityORCID 0000-0002-9898-1489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Charis EngiD· 1 shared Dapeng XiongiD· 1 shared Dongjin LeeiD· 1 shared Feixiong ChengiD· 1 shared Haiyuan YuiD· 1 shared Jin Joo KangiD· 1 shared Joseph LoscalzoiD· 1 shared Junfei ZhaoiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Charis EngORCID

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1 paper

Recent·Most cited

Structurally-informed human interactome reveals proteome-wide perturbations by disease mutations

Dapeng Xiong, Yunguang Qiu, Junfei Zhao, Yadi Zhou, Dongjin Lee, Shobhita Gupta, Mateo Torres, Weiqiang Lü, Siqi Liang, Jin Joo Kang, Charis Eng, Joseph Loscalzo, Feixiong Cheng, Haiyuan Yu

The paper introduces PIONEER, a deep learning framework for predicting protein-protein interfaces, and shows disease mutations are enriched in these interfaces, identifying oncoPPIs linked to cancer survival and drug responses.

bioRxiv · Apr 24, 2023 · PreprintBioinformatics