Author

Shahrzad Bakhtiar

Goethe University FrankfurtORCID 0000-0002-9898-1542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Assay:proteomics· 1

Frequent Co-Authors

Leon Maximilian LueckiD· 2 shared Anne SpangiD· 1 shared Celia Kaffenberger· 1 shared Christoph KönigsiD· 1 shared Daan OverwijniD· 1 shared Emilia Salzmann‐Manrique· 1 shared Julia Fekadu· 1 shared Laura M. MoseriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Leon Maximilian LueckORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 10, 2024

Abatacept treatment in LRBA deficient patients results in an increase in circulating FoxP3+ Helios + natural Treg

Sabine Donhauser, Emilia Salzmann‐Manrique, Leon Maximilian Lueck…·Shahrzad Bakhtiar

This study examines Treg subpopulations in LRBA-deficient patients before, during, and after abatacept treatment, finding increased natural Treg levels and decreased sIL2R levels.

DOI 10.1101/2024.02.10.579765

humanflow cytometry

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ImmunologybioRxivPreprintFeb 7, 2024

Endosomal LRBA regulates the endo-lysosomal pathway

Viktória Szentgyörgyi, Leon Maximilian Lueck, Daan Overwijn…·Shahrzad Bakhtiar

This study identifies LRBA's role in regulating the endosomal-lysosomal pathway by controlling Rab4+ endosome traffic, leading to enlarged endolysosomes in LRBA-deficient patients.

DOI 10.1101/2024.02.07.579084

humanproteomics

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