Author

Brianna K. Barry

Johns Hopkins UniversityORCID 0000-0002-9900-1841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Andrew E. JaffeiD· 3 shared Leonardo Collado‐TorresiD· 3 shared Joel E. KleinmaniD· 2 shared Keri MartinowichiD· 2 shared Kristen R. MaynardiD· 2 shared Louise A. Huuki-MyersiD· 2 shared Madhavi TippaniiD· 2 shared Matthew Nguyen TraniD· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Andrew E. JaffeORCID

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Author profile →

3 papers

Recent·Most cited

Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain

Matthew Nguyen Tran, Kristen R. Maynard, Abby Spangler, Louise A. Huuki-Myers, Kelsey D. Montgomery, Vijay Sadashivaiah, Madhavi Tippani, Brianna K. Barry, Dana B. Hancock, Stephanie C. Hicks, Joel E. Kleinman, Thomas M. Hyde, Leonardo Collado‐Torres, Andrew E. Jaffe, Keri Martinowich

The paper uses snRNA-seq to analyze five human brain regions, identifies novel neuronal subpopulations, and links them to psychiatric and substance use risks.

Neuron · Sep 27, 2021Peer-reviewedNeuroscience

SPEAQeasy: a Scalable Pipeline for Expression Analysis and Quantification for R/Bioconductor-powered RNA-seq analyses

Nicholas J. Eagles, Emily E. Burke, Jacob Leonard, Brianna K. Barry, Joshua M. Stolz, Louise A. Huuki-Myers, BaDoi N. Phan, Violeta Larios‐Serrato, Everardo Gutiérrez-Millán, Israel Aguilar-Ordóñez, Andrew E. Jaffe, Leonardo Collado‐Torres

SPEAQeasy provides a user-friendly, scalable RNA-seq pipeline that simplifies data processing and connects to R/Bioconductor tools for downstream analysis.

BMC Bioinformatics · May 1, 2021Peer-reviewedBioinformatics

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

Kristen R. Maynard, Leonardo Collado‐Torres, Lukas M. Weber, Cedric R. Uytingco, Brianna K. Barry, Stephen R. Williams, Joseph L Catallini II, Matthew Nguyen Tran, Zachary Besich, Madhavi Tippani, Jennifer G. Chew, Yifeng Yin, Joel E. Kleinman, Thomas M. Hyde, Nikhil Rao, , Andrew E. Jaffe

The paper maps spatial gene expression in the human dorsolateral prefrontal cortex using spatial transcriptomics and identifies layer-specific gene expression patterns linked to neuropsychiatric disorders.

Nature Neuroscience · Feb 8, 2021Peer-reviewedNeuroscience