Author

Zhengyu Jing

ShanghaiTech UniversityORCID 0000-0002-9907-512XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:CRISPR screen· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Bo LiuiD· 2 shared Junjun Lv· 2 shared Shaoshuai MaoiD· 2 shared Tian H. ChiiD· 2 shared Aibing Liang· 1 shared Bryan C. DickinsoniD· 1 shared Dingyu Cao· 1 shared Ge Wei· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersGenomics

Bo LiuORCID

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Author profile →

3 papers

Recent·Most cited

Optimized iMAP CRISPR Perturbation Illuminates Context-Specific Functions of RNA Modification Factors

Ge Wei, Zhengyu Jing, Weikai Wang, Bo Liu, Shaoshuai Mao, Junjun Lv, Xiaoming Zhang, Dingyu Cao, Ruilin Sun, Aibing Liang, Tian Chi

The paper optimizes the iMAP CRISPR platform to reduce recombination bias, profiles RNA modification factors across mouse tissues, and identifies context-specific functions with therapeutic implications.

bioRxiv · Jul 24, 2025 · PreprintGenomics

Expanding RNA editing toolkit using an IDR-based strategy

Minghui Di, Junjun Lv, Zhengyu Jing, Yijie Yang, Kunlun Yan, Jianguo Wu, Jianyang Ge, Simone Rauch, Bryan C. Dickinson, Tian H. Chi

The paper introduces a strategy to enhance C>U RNA editors using IDR-derived domains, improving both on- and off-target editing efficiency.

Molecular Therapy — Nucleic Acids · Apr 16, 2024Peer-reviewedMolecular Biology

Novel mosaic mice with diverse applications

Yuxin Chen, Shaoshuai Mao, Bo Liu, Zhengyu Jing, Ying Zang, Jing Xia, Jianlong Sun, Tian H. Chi

This paper introduces MARC mice, which allow studying multiple genes per mouse but one gene per cell, enabling efficient functional genomics research.

bioRxiv · Mar 21, 2020 · PreprintGenetics