Author

Ruilin Sun

Shanghai Model Organisms (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Aibing Liang· 1 shared Bo LiuiD· 1 shared Dingyu Cao· 1 shared Ge Wei· 1 shared Jiaxuan Shao· 1 shared Junjun Lv· 1 shared Lei Ci· 1 shared Lijun ZhouiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aibing Liang

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Establishment of a Systemic Lupus Erythematosus Mouse Model in Humanized CD3/CD19 Mice and Evaluation of the Efficacy of a Human Bispecific Antibody

Yaqi Du, Lijun Zhou, Jiaxuan Shao, Yanling Wang, Menghan Cui, Shuang Li, Yu‐Chieh Su, Lei Ci, Ruilin Sun

This paper establishes a humanized CD3/CD19 mouse model of SLE and evaluates the efficacy of a human bispecific antibody in treating the disease.

bioRxiv · Aug 21, 2025 · PreprintImmunology

Optimized iMAP CRISPR Perturbation Illuminates Context-Specific Functions of RNA Modification Factors

Ge Wei, Zhengyu Jing, Weikai Wang, Bo Liu, Shaoshuai Mao, Junjun Lv, Xiaoming Zhang, Dingyu Cao, Ruilin Sun, Aibing Liang, Tian Chi

The paper optimizes the iMAP CRISPR platform to reduce recombination bias, profiles RNA modification factors across mouse tissues, and identifies context-specific functions with therapeutic implications.

bioRxiv · Jul 24, 2025 · PreprintGenomics