eIF4E phosphorylation recruits β-catenin to mRNA cap and selectively promotes Wnt pathway translation in dentate gyrus LTP maintenance in vivo
Sudarshan S. Patil, Kleanthi Chalkiadaki, Tadiwos Feyissa Mergiya, Konstanze Simbriger, Inês S. Amorim, Shreeram Akerkar, Christos G. Gkogkas, Clive R. Bramham
This study shows that eIF4E phosphorylation is essential for maintaining dentate gyrus LTP in vivo by recruiting β-catenin to the mRNA cap and enhancing Wnt pathway translation.
bioRxiv · Sep 28, 2022 · PreprintNeuroscience