Monocyte Metabolic Plasticity and Cytokine Production Differentiate Latent TB Infection from Active Disease
Gráinne Jameson, Isabella Batten, Adam H. Dyer, C. Geoghegan, Moninne Murray, Niamh McDonnell, Dearbhla M Murphy, Sarah A. Connolly, Anne Marie McLaughlin, Cilian Ó Maoldomhnaigh, Laura E. Gleeson, Joseph Keane, Sharee A. Basdeo
This study compares monocyte phenotypes, function, and metabolism in latent TB infection, active TB disease, and healthy controls, finding distinct metabolic and cytokine profiles that differentiate the conditions.
Journal of Infection · Apr 26, 2026Peer-reviewedImmunology