Author

Kwontae You

Illumina (United States)ORCID 0000-0002-9928-6779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A Blocker· 1 shared Adam J. LittermaniD· 1 shared Andrei V. BakiniD· 1 shared Ann C Huang· 1 shared Ashton TengiD· 1 shared Atina G. CotéiD· 1 shared Christopher J Graves· 1 shared Ci ChuiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

A Blocker

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3 papers

Recent·Most cited

A Proteome-Wide Gain-of-Function Atlas Mapping the Landscape of Chemotherapy Response

Kyeong Beom Jo, Mohammed Alruwaili, Da-Eun Kim, Yongjun Koh, H Kim, Kwontae You, Ji‐Sun Kim, Saba Sane, Yanqi Guo, Jacob P Wright, Maricris N. Naranjo, Atina G. Coté, Frederick P. Roth, DAVID EDWIN HILL, Jung‐Hyun Choi, , Dae‐Kyum Kim

This study creates a proteome-wide gain-of-function atlas to map chemotherapy responses and identifies drug combinations to overcome resistance.

bioRxiv · Sep 2, 2025 · PreprintSystems Biology

X-Atlas/Orion: Genome-wide Perturb-seq Datasets via a Scalable Fix-Cryopreserve Platform for Training Dose-Dependent Biological Foundation Models

Ann C Huang, Tsung-Han S. Hsieh, Jiang Zhu, Jackson Michuda, Ashton Teng, Soohong Kim, Elizabeth M Rumsey, Sharon K Lam, Ikenna Anigbogu, Philip Wright, Mohamed Ameen, Kwontae You, Christopher J Graves, Hyunsung John Kim, Adam J. Litterman, , Ci Chu

The paper introduces a scalable Perturb-seq platform called FiCS Perturb-seq and releases X-Atlas/Orion, a large Perturb-seq atlas, to improve foundation model development through dose-dependent genetic effects.

bioRxiv · Jun 11, 2025 · PreprintGenomics

AQ-seq: Accurate quantification of microRNAs and their variants

Haedong Kim, Jimi Kim, Kijun Kim, Hyeshik Chang, Kwontae You, V. Narry Kim

AQ-seq improves miRNA quantification by reducing ligation bias, revealing new miRNA variants and modifications.

Nucleic Acids Research · Dec 15, 2018Peer-reviewedMolecular Biology