Mohammed Alruwaili

A Sequential Triple-Drug Strategy for Selective Targeting of p53-Mutant Cancers

This paper develops a sequential triple-drug strategy targeting p53 mutant cancers, showing it effectively induces cell death while minimizing toxicity to normal cells.

A Proteome-Wide Gain-of-Function Atlas Mapping the Landscape of Chemotherapy Response

This study creates a proteome-wide gain-of-function atlas to map chemotherapy responses and identifies drug combinations to overcome resistance.

p38 blockade reverses the immune suppressive tumor microenvironment in metastatic breast cancer

This study shows that blocking p38 reduces metastasis in breast cancer by reversing immune suppression in the tumor microenvironment, primarily through effects on CD8+ T cells and myeloid cells.