Author

Shevan Silva

University of AucklandORCID 0000-0002-9942-1897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adam Vorn Patterson· 1 shared Alisha R. DabbiD· 1 shared Amir AshoorzadehiD· 1 shared Christopher P. GuiseiD· 1 shared Emily Liu· 1 shared Ian F. HermansiD· 1 shared Jeff Bruce SmailliD· 1 shared Kathryn J. FarrandiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam Vorn Patterson

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintFeb 24, 2025

Tarloxotinib targets tumor hypoxia to improve therapeutic efficacy of immune checkpoint inhibition in a TLR9 dependent manner

Zhe Fu, Victoria Jackson-Patel, Kathryn J. Farrand…·Adam Vorn Patterson

This paper shows that tarloxotinib, a hypoxia-activated prodrug, reduces tumor hypoxia and enhances immune checkpoint inhibitor efficacy through TLR9-dependent mechanisms in multiple tumor models.

DOI 10.1101/2025.02.24.635378

mousebulk RNA-seq

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