Anti-PTHrP blockade limits CD8+ T-cell exhaustion in anti-cancer immunotherapy
Bastien Moës, Yunfeng Gao, Ekaterina P. Demina, Richard B. Kremer, Christopher E. Rudd
This study shows that anti-PTHrP therapy reduces T-cell exhaustion and enhances cytolytic protein expression in melanoma, suggesting it could improve cancer immunotherapy.
bioRxiv · Oct 23, 2024 · PreprintImmunology