Author

Richard B. Kremer

McGill University Health CentreORCID 0000-0002-7053-2139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Christopher E. RuddiD· 2 shared Adı́lson GuilhermeiD· 1 shared Ami GrunbaumiD· 1 shared Atena Nemati· 1 shared Bastien Moës· 1 shared Calvin Johnson· 1 shared Catalin Milhalcioiu· 1 shared Chen LiuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

Christopher E. RuddORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis

Nikita Bhalerao, Yamini Ogoti, Jessica Peura, Calvin Johnson, Qingbo Chen, Ekaterina D. Korobkina, Faith N. Keller, Maximilian D. Wengyn, Robert J. Norgard, Claire Shamber, Kelsey A. Klute, Dominick J. DiMaio, Karine Sellin, Paul M. Grandgenett, Rui Li, , Jason Robert Pitarresi

This study identifies PTHrP as a driver of pancreatic cancer cachexia by suppressing adipose de novo lipogenesis, showing that blocking PTHrP-PTH1R signaling reduces wasting in mouse models.

bioRxiv · Jun 3, 2025 · PreprintCancer Biology

The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells

Thai Hien Tu, Fatima Ezzahra Bennani, Nasser Masroori, Chen Liu, Atena Nemati, Nicholas Rozza, Ami Grunbaum, Richard B. Kremer, Catalin Milhalcioiu, Denis‐Claude Roy, Christopher E. Rudd

The paper identifies a SARS-CoV-2 S2 protein-derived peptide (P3) with super-antigen-like properties that stimulate T-cells and induce proinflammatory cytokines in mice.

Communications Biology · Jan 6, 2025Peer-reviewedImmunology

Anti-PTHrP blockade limits CD8+ T-cell exhaustion in anti-cancer immunotherapy

Bastien Moës, Yunfeng Gao, Ekaterina P. Demina, Richard B. Kremer, Christopher E. Rudd

This study shows that anti-PTHrP therapy reduces T-cell exhaustion and enhances cytolytic protein expression in melanoma, suggesting it could improve cancer immunotherapy.

bioRxiv · Oct 23, 2024 · PreprintImmunology