Zhengda Li

Activation thresholds set the speed of biochemical trigger waves

The paper measures apoptotic wave speeds in cell extracts and extends Luther's equation to include an activation threshold, showing it determines wave speed.

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

The paper creates an organism-wide hormone signaling atlas in mouse lemurs, identifying hormone-producing and -target cells and revealing species-specific rewiring and conservation compared to humans and mice.

High-resolution mapping of the period landscape reveals polymorphism in cell cycle frequency tuning

The paper maps the cell cycle period landscape using synthetic cells and identifies polymorphic responses to PP2A inhibition.

A robust and tunable mitotic oscillator in artificial cells

This paper develops an artificial single-cell system to study mitotic oscillations, showing sustained oscillations over 30 cycles and highlighting energy supply's role in cell cycles.