James E. Ferrell

The paper measures apoptotic wave speeds in cell extracts and extends Luther's equation to include an activation threshold, showing it determines wave speed.

The paper shows that single-cell gene expression responses in mammalian systems are all-or-none due to stable epigenetic variability, not bursty transcription or bistability.

This study analyzes global trends in human birth and death seasonality, finding climate-related shifts in reproductive timing due to rising temperatures.

The paper examines temperature scaling in the early embryonic cell cycle across multiple species, finding similar activation energies and explaining deviations using computational models and experimental data.

The paper shows that enhancer-promoter communication scales with genomic distance in a gene-specific manner, independent of 3D contact frequency or chromatin state.

The paper investigates trigger wave speed robustness in Xenopus extracts, finding it invariant despite cytoplasmic concentration changes and proposing a model explaining this behavior.

The paper shows that injury triggers ultrafast Erk signal propagation in planarians, mediated by body-wall muscles, which is essential for regeneration.

The paper tests how cytoplasmic protein concentration affects mRNA translation and degradation in Xenopus extracts, finding different optimal concentrations for synthesis and degradation.

This paper uses a mouse lemur transcriptomic atlas to identify new genes, splice junctions, and disease-related features, highlighting their relevance to primate biology and human disease.

Portal integrates large-scale single-cell datasets efficiently and accurately by preserving biological variation across samples, platforms, and species.

The paper creates an organism-wide hormone signaling atlas in mouse lemurs, identifying hormone-producing and -target cells and revealing species-specific rewiring and conservation compared to humans and mice.

The paper creates a comprehensive cell atlas of mouse lemurs using single-cell RNA sequencing, identifying over 750 cell types and comparing their molecular profiles to humans, mice, and macaques.