Patient-specific "Physical Twin" artery-on-chip platform reveals complex flow-dependent VWF mechanobiology and guides personalized antithrombotic therapy
Yunduo Charles Zhao, Y Liu, Zihao Wang, Naveen Eugene Louis, Nicole Alexis Yap, Arian Nasser, Allan Sun, Yiyao Catherine Chen, Alexander Dupuy, Eugene Marfo Obeng, Mary Meltem Kavurma, Ken S. Butcher, Xin Xu, Jingjing You, Freda H. Passam, , Lining Arnold Ju
The paper develops a patient-specific artery-on-chip platform to study flow-dependent VWF mechanobiology and guide personalized antithrombotic therapy.
bioRxiv · May 15, 2026 · PreprintBioengineering