Author

Mary Meltem Kavurma

The Heart Research InstituteORCID 0000-0001-7353-0932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander DupuyiD· 2 shared Freda H. PassamiD· 2 shared Siân Peta CartlandiD· 2 shared Alexander Ruvantha PintoiD· 1 shared Allan SuniD· 1 shared Arian NasseriD· 1 shared Callum B. HoulahaniD· 1 shared Cesar L. MorenoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

Alexander DupuyORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 15, 2026

Patient-specific "Physical Twin" artery-on-chip platform reveals complex flow-dependent VWF mechanobiology and guides personalized antithrombotic therapy

Yunduo Charles Zhao, Y Liu, Zihao Wang…·Lining Arnold Ju

The paper develops a patient-specific artery-on-chip platform to study flow-dependent VWF mechanobiology and guide personalized antithrombotic therapy.

1 citation

humanexperimental assay

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PathologybioRxivPreprintSep 22, 2025

Mitochondrial Dysfunction in Endothelial Cells Drives Greater Vascular Impairment in Females with Diabetes-Associated Peripheral Artery Disease

Siân Peta Cartland, Elaina Kelland, Natalie Le…·Mary Meltem Kavurma

This study identifies sex-specific mitochondrial dysfunction in endothelial cells of diabetic PAD patients, showing that MitoQ improves vascular function in females.

DOI 10.1101/2025.09.22.677648

mousehuman

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Cell BiologyJournal of Clinical InvestigationPeer-reviewedAug 15, 2025

Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus

Yvonne X. Kong, Rajan Rehan, Cesar L. Moreno…·Freda H. Passam

This study identifies SEC61B as a regulator of calcium flux and platelet hyperreactivity in diabetes by linking ER stress to increased SEC61B expression and calcium leak.

12 citationstop 2%

humanmouse

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