Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms
Paul B Conway, Livia Autore, Andrea Muñoz Zamora, Antoine Harel, Zijun Wang, Arman A. Tavallaei, Stephen M. Winston, Clara Ortega‐de San Luis, James D. O’Leary, Mark A. Brimble, Gisella Vetere, Tomás J. Ryan
The paper shows that innate fear responses to visual looming stimuli in mice can be reduced through repeated exposure and that hippocampal engrams are required for learned fear responses.
PLoS Biology · Sep 24, 2025Peer-reviewedNeuroscience