Estrogen-related receptor gamma is required for normal auditory innervation and is essential for hearing.
Shri V. Seshadri, Neil J. Ingham, Rhianna R. Mackenzie, Adam J. Carlton, Stuart L. Johnson, Darya Alcock, Anwen Bullen, Katie E. Smith, Walter Marcotti, Karen P. Steel, Lisa S. Nolan
This study identifies ESRRG as essential for normal auditory innervation and hearing by showing that its loss causes early-onset hearing loss and synaptic defects in mice.
bioRxiv · May 5, 2026 · PreprintNeuroscience