Adam J. Carlton

This study shows that hair cell function declines with age in mice before hearing loss is detectable, challenging the idea that stereocilia are the most fragile part of sensory cells in aging.

This study investigates how intrinsic lateral olivocochlear (iLOC) neuron excitability changes with age and rewiring, showing distinct biophysical shifts driven by Kv4, Kv2, and Kv3 currents, independent of hair cell dysfunction.

This study identifies ESRRG as essential for normal auditory innervation and hearing by showing that its loss causes early-onset hearing loss and synaptic defects in mice.

This study investigates the role of Neuroplastin in mammalian hearing, showing that only the Np55 isoform is essential for cochlear hair cell function and that its absence interacts genetically with Cdh23 mutations to cause hearing loss.