Author

Daniel de Castro Assumpção

Northwestern UniversityORCID 0000-0002-9973-3241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Danielle Tullman‐ErcekiD· 2 shared Nolan W. KennedyiD· 2 shared Aline Carvalho da Costa· 1 shared Carolyn E. MillsiD· 1 shared Emma S. VinokouriD· 1 shared James B. JungiD· 1 shared Kaavya Butaney· 1 shared Madeline M. MillsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

Danielle Tullman‐ErcekORCID

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2 papers

Recent·Most cited

BiophysicsNew BiotechnologyPeer-reviewedMar 14, 2026

Process for Standardizing and Assessing the Parameters Governing MS2 Virus-Like Particle Reassembly around Nucleic Acid Cargo

Daniel de Castro Assumpção, Emma S. Vinokour, Madeline M. Mills…·Danielle Tullman‐Ercek

This paper introduces a standardized framework to quantify MS2 VLP reassembly yields and identifies key parameters affecting reassembly efficiency.

3 citations

statistical modelbenchmarking

𝕏 PostBluesky

Synthetic BiologyACS NanoPeer-reviewedOct 29, 2025

Synthetic Rewiring of Virus-Like Particles via Circular Permutation Enables Modular Peptide Display and Protein Encapsulation

Shiqi Liang, Kaavya Butaney, Daniel de Castro Assumpção…·Danielle Tullman‐Ercek

The paper demonstrates the use of circular permutation to engineer virus-like particles, enabling peptide display and protein encapsulation through a comprehensive library and cryo-EM validation.

5 citations

protein structureexperimental assay

𝕏 PostBluesky