BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Biochemical and structural basis of Dicer helicase function unveiled by resurrecting ancient proteins
Adedeji M. Aderounmu, Josephine Maus-Conn, Claudia D. Consalvo…·Brenda Bass
This study reconstructs ancient Dicer helicases to uncover how ATP hydrolysis drives dsRNA translocation and cleavage, revealing evolutionary changes in helicase function across species.