Alanine dependence of trans-translation contributes to riboregulation of mycobacterial antibiotic recalcitrance genes
Andrea Majstorović, Hélène Botella, Sarah M. Schrader, Yaroslav Lavrynchuk, Xinguo Chen, Enkai Jin, Jason Taslim, Rudy Antoine, Alain R. Baulard, Christophe Guilhot, Przemysław Płociński, Sandra L. Wolin, Julien Vaubourgeix
The paper identifies alanine's role in linking trans-translation to WhiB7-mediated antibiotic resistance and recalcitrance in Mycobacterium smegmatis.
bioRxiv · Oct 10, 2025 · PreprintMicrobiology