Systems BiologybioRxivPreprint
Systems genetics identifies ETS1 as a stress-dependent regulator of adipocyte insulin action and heme-iron homeostasis
Yi Lin Jiang, Kristen C. Cooke, Harry B. Cutler…·Søren Madsen
DOI 10.64898/2026.09.01.748508
Author
The University of SydneyORCID 0000-0003-0012-2529Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yi Lin Jiang, Kristen C. Cooke, Harry B. Cutler…·Søren Madsen
Stewart W. C. Masson, Rebecca C. Simpson, Harry B. Cutler…·David Ernest James
This study identifies a genetic locus affecting insulin sensitivity in mice, showing that Defa26 modulates glucose homeostasis through microbiome interactions.
Stewart W. C. Masson, Søren Madsen, Kristen C. Cooke…·David Ernest James
The paper identifies small molecules that reverse insulin resistance in mouse skeletal muscle by integrating systems genetics and chemical screening.