Author

Vincent M. Lowe

University of Maryland, BaltimoreORCID 0000-0003-3651-8461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel Joseph DeredgeiD· 2 shared Ally K. SmithiD· 1 shared Caren L. Freel MeyersiD· 1 shared Eucolona M. TociiD· 1 shared Fabrizio MarinelliiD· 1 shared Rinky D. ParakraiD· 1 shared Sandra Byju· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

Daniel Joseph DeredgeORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 29, 2026

Multi-Ensemble Reweighting Enables Structural Interpretation of Differential HDX-MS

Sandra Byju, Vincent M. Lowe, Daniel Joseph Deredge, Fabrizio Marinelli

This paper introduces a multi-ensemble reweighting method for HDX-MS data to improve structural interpretation by accounting for deuterium loss, showing better accuracy than conventional methods.

DOI 10.64898/2026.10.28.762400

proteomicsstatistical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 16, 2026

MInt-HDX: Leveraging Hydrogen-Deuterium Exchange Mass Spectrometry and Machine-Learning to Improve Protein-Ligand Docking.

Vincent M. Lowe, Ally K. Smith, Rinky D. Parakra…·Daniel Joseph Deredge

MInt-HDX improves protein-ligand docking by integrating HDX-MS data with machine learning and physics-based methods to enhance docking accuracy and ligand pose ranking.

DOI 10.64898/2026.07.14.738285

proteomicsmachine learning (classical)

𝕏 PostBluesky