Emanuela Monni

This study develops a method to efficiently generate human oligodendrocytes from induced pluripotent stem cells, which can form functional myelinating grafts in adult human brain tissue.

The paper examines how age and sex influence gene expression in human monocyte subtypes related to neuroinflammation and regeneration, identifying age- and sex-dependent gene changes.

This study generates human cortical neurons from hES cells via NGN2 overexpression and shows their integration into stroke-injured rat brains.

This study shows L1 retrotransposons contribute to human brain transcriptome complexity and functional diversification through cell-type specific transcripts and regulatory RNAs.

This study shows human iPS cell-derived oligodendrocytes can remyelinate adult rat and human cortical neurons in vitro and in vivo.

This study shows HIF-2α regulates neural crest stemness and development, with implications for neuroblastoma.