Molecular BiologyJournal of Cell SciencePeer-reviewed
Variability in mitochondrial import, mitochondrial health and mtDNA copy number using Type II and Type V CRISPR effectors
Zuriñe Antón, Grace Mullally, Holly C. Ford…·Jon D. Lane
This study evaluates the effectiveness of different CRISPR effectors for targeting mitochondria, finding that LbCas12a shows better targeting and tolerance than Cas9 variants.