Abigail R. Gerhold

Expanding the C. elegans toolkit with gonad explants

This study introduces C. elegans gonad explants as a system for studying germline development with live-cell imaging and drug treatment.

The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the C. elegans germ line

The paper shows LIN-5/NuMA regulates spindle orientation and tissue organization in C. elegans germ cells through polarized cortical localization.

Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells

This study shows that insulin signaling delays mitosis in C. elegans germline stem and progenitor cells in a non-autonomous manner, while caloric restriction affects mitosis through AMPK.

Widely used mutants of eiger, encoding the Drosophila Tumor Necrosis factor, carry additional mutations in the NimrodC1 phagocytosis receptor

The paper identifies additional mutations in the NimrodC1 phagocytosis receptor in widely used egr3 mutant Drosophila strains, which may affect phagocytic function.

Spindle assembly checkpoint strength is governed by cell size and PAR-mediated cell fate determination in C. elegans

This study shows that SAC strength in C. elegans is influenced by cell size and cell fate, with germline cells showing increased SAC activity due to PAR-mediated fate determination.