Takefumi Negishi

The paper investigates the distinct and cooperative roles of multiple Wnt ligands and receptors in regulating cell polarity orientation in C. elegans.

This paper develops a scAb-AID2 system for conditional protein degradation without requiring degron tags, demonstrating its effectiveness in human and C. elegans cells.

The paper shows LIN-5/NuMA regulates spindle orientation and tissue organization in C. elegans germ cells through polarized cortical localization.

The paper identifies a Nodal/Eph signalling relay that controls the transition from apical constriction to apico-basal shortening during ascidian endoderm invagination, without affecting cell fate specification.