Romain Brette

Paramecium tetraurelia alternates fast swimming with minutes-long surface immobilization when bacteria are present; stops require calcium influx and come from halting locomotor cilia while oral cilia keep beating.

This study shows that brief monocular deprivation induces homeostatic changes in intrinsic neuronal excitability in thalamic relay cells, involving Kv1 and Nav1 channel regulation and electrical coupling.

The paper trains a convolutional network to estimate the vertical position of Paramecium from single-camera bright field images using a dataset generated from a tilted slide setup.

This paper develops a theoretical framework to quantify the electrical impact of axo-axonic synapses on action potential initiation, showing that synaptic inputs shift the threshold proportionally to synaptic conductance.

This study shows that visual activity increases intrinsic excitability in thalamic relay neurons through LTP-IE, involving calcium influx and PKA activation, and links this to visual plasticity and amblyopia.

The paper develops a biophysical model of Paramecium's action potential and couples it to kinematic parameters to simulate autonomous behavior and environmental interactions.

The paper shows that increasing axial resistance at the axon hillock lowers the spike threshold in L5 pyramidal neurons, supporting resistive coupling theory.

The paper measures axial current in mouse retinal ganglion cells to show how the axon initial segment supports reliable action potential backpropagation through high sodium conductance and charge preservation.

The paper shows axonal sodium channels transmit input synchrony levels to postsynaptic cells by modulating action potential amplitude, enhancing synaptic transmission for synchronous inputs.

The paper derives a theoretical formula linking axon initial segment geometry and sodium conductance density to somatic voltage threshold, showing how AIS position affects excitability.

The paper presents a model showing how ankle stiffness and spinal sensorimotor gains coadapt to maintain balance during neural delays, with implications for aging and balance strategies.

Brian 2 is a neural simulator that simplifies model definition and improves performance through runtime code generation, demonstrated with various examples.

This study shows elderly fallers can achieve balance recovery similar to non-fallers by adjusting posture in anticipation of perturbations.

The paper argues that the neural coding metaphor is misleading as it fails to capture the causal and informational structure of the brain.

The paper investigates how the axon initial segment contributes to extracellular action potential signatures, showing dipole formation and changes in waveform based on initiation site.

The paper demonstrates how to model neuron-glia interactions using the Brian 2 simulator, highlighting its flexibility for simulating glial physiology and astrocyte influence on neural activity.

This paper argues that posture is adjusted to provide impetus for movement rather than counteracting gravity, showing how postural adjustments enable torque for movement.