Rebecca A. Piskorowski

This study shows that an obesogenic diet impairs social memory in mice by altering hippocampal CA2 excitability and oxytocin signaling, with specific effects on endocannabinoid plasticity and social novelty discrimination.

The paper examines dendritic morphology of CA2 and CA1 pyramidal neurons, finding gradual morphological changes along the radial axis that suggest a continuum rather than distinct subtypes.

This paper creates a knockin mouse model with a K198R mutation in CK2 kinase, showing ASD-like behaviors and synaptic deficits, validating it as a model for Okur-Chung Neurodevelopmental Syndrome.

The paper shows core-N-glycans are abundant on neuronal surfaces and impair NMDA receptor-dependent synaptic plasticity by reducing synaptic AMPA receptor expression and slowing AMPA receptor desensitization.

This study identifies how hypothalamic SuM input modulates hippocampal CA2 circuitry, enhancing firing precision and influencing CA1 activity through synchronized inhibition.

This study shows that cannabinoids induce long-term depression by remodeling presynaptic vesicle pools through actomyosin contractility.