Qiujie Liu

DeepD is a genome foundation model that enables accurate sequence-to-function prediction and controllable genome-scale sequence generation across domains of life.

This study identifies miR156 and SPL genes' roles in wheat heading time regulation through interactions with photoperiod, vernalization, and gibberellin pathways, and develops genetic resources to fine-tune heading time.

The paper sequences 4.3 million promoter mutations and 4.7 million coding mutations in wheat to understand gene function and improve agronomic traits.