Germán Burguener

A genetic toolkit to reduce wheat immunogenicity and incidence of celiac disease

This study generates non-transgenic wheat genetic stocks with reduced immunogenic epitopes to develop celiac disease-safe wheat varieties.

Spatial and single-cell expression analyses reveal complex expression domains in early wheat spike development

Combining 99-gene smFISH across 48,225 cells with scRNA-seq of 26,009 cells maps 21 spatial expression domains and imputes 74,464 genes in early tetraploid wheat spikes.

Deletion of wheat alpha-gliadins from chromosome 6D improves gluten strength and reduces immunodominant celiac disease epitopes

This study deletes wheat alpha-gliadins from chromosome 6D to improve gluten strength and reduce celiac disease epitopes.

Natural alleles of LEAFY and WAPO1 interact to regulate spikelet number per spike in wheat

This study identifies natural alleles of LEAFY and WAPO1 that interact to regulate spikelet number per spike in wheat, suggesting a genetic combination for improving grain yield.

Sequencing 4.3 million mutations in wheat promoters to understand and modify gene expression

The paper sequences 4.3 million promoter mutations and 4.7 million coding mutations in wheat to understand gene function and improve agronomic traits.

De novo assembly of the black flounder genome. Why do pleuronectiformes have such a small genome size?

This study assembles the black flounder genome and investigates why Pleuronectiformes have a small genome size, finding that reduced transcript size, particularly exon number and large introns, contributes to this reduction.

A second generation capture panel for cost-effective sequencing of genome regulatory regions in wheat and relatives

The paper develops an updated capture panel for sequencing regulatory regions in wheat and related species, improving specificity and coverage over previous methods.