Cancer BiologybioRxivPreprint
REST-AKT-SOX2 axis controls neuronal lineage state and Midkine-mediated communication in SHH-medulloblastoma.
Ashutosh Singh, Lei Guo, Jyothishmathi Swaminathan…·Vidya Gopalakrishnan
This study identifies the REST-AKT-SOX2 axis as a key regulator of stem/progenitor identity and Midkine-mediated communication in SHH medulloblastoma, highlighting it as a potential therapeutic target.
DOI 10.64898/2026.04.06.716597