Pharmacology & ToxicologyThe Journal of Infectious DiseasesPeer-reviewed
Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice
Jennie Ruelas Castillo, Valentina Guerrini, Darla Quijada…·Petros C. Karakousis
This study evaluates two compounds that reduce triglyceride content in Mtb-infected macrophages but finds they do not reduce bacterial burden or inflammation in infected mice.
3 citations