MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
Dario Akaberi, Monireh Pourghasemi Lati, Janina Krambrich…·Johan Lennerstrand
This paper identifies potent SARS-CoV-2 main protease inhibitors from a DNA-encoded chemical library using affinity-based selection, achieving an IC50 of 30 nM for compound SLL11.
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