Åke Lundkvist

This study shows that heparanase (Hpa) restricts Zika virus (ZIKV) infection by degrading the viral envelope protein, while ZIKV downregulates Hpa to counteract this effect.

This paper identifies potent SARS-CoV-2 main protease inhibitors from a DNA-encoded chemical library using affinity-based selection, achieving an IC50 of 30 nM for compound SLL11.

This study traces the evolutionary origins and molecular changes of a chikungunya virus outbreak in Thailand, identifying mutations linked to increased virulence and transmission.

The paper identifies a critical epitope on PUUV Gc targeted by neutralizing antibodies and shows that mutations in this region confer neutralization escape.