Author

Janina Krambrich

Uppsala UniversityORCID 0000-0002-5061-7143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:virus· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Åke LundkvistiD· 2 shared Anja SandströmiD· 1 shared Cixiu LiiD· 1 shared Dario AkaberiiD· 1 shared Emilia Strandback· 1 shared Filip MihaličiD· 1 shared Grace NeilseniD· 1 shared Hjalmar Gullberg· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Åke LundkvistORCID

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2 papers

Recent·Most cited

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedAug 28, 2024

Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Dario Akaberi, Monireh Pourghasemi Lati, Janina Krambrich…·Johan Lennerstrand

This paper identifies potent SARS-CoV-2 main protease inhibitors from a DNA-encoded chemical library using affinity-based selection, achieving an IC50 of 30 nM for compound SLL11.

5 citations

virusexperimental assay

𝕏 PostBluesky

MicrobiologyPLoS neglected tropical diseasesPeer-reviewedJul 26, 2024

The evolutionary and molecular history of a chikungunya virus outbreak lineage

Janina Krambrich, Filip Mihalič, Michael W. Gaunt…·John H.‐O. Pettersson

This study traces the evolutionary origins and molecular changes of a chikungunya virus outbreak in Thailand, identifying mutations linked to increased virulence and transmission.

38 citationstop 1%

viruswhole-genome sequencing

𝕏 PostBluesky