Author

Grace Neilsen

Emory UniversityORCID 0000-0001-9344-1160Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

Stefan G. SarafianosiD· 2 shared Åke LundkvistiD· 1 shared Andres Emanuelli CastaneriD· 1 shared Anja SandströmiD· 1 shared Dario AkaberiiD· 1 shared Emilia Strandback· 1 shared Hjalmar Gullberg· 1 shared Janina KrambrichiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Stefan G. SarafianosORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 24, 2025

Characterization of antiviral compounds using Bio-Layer Interferometry

Zachary C. Lorson, William M. McFadden, Grace Neilsen…·Stefan G. Sarafianos

This paper optimizes Bio-Layer Interferometry (BLI) protocols to measure binding affinities of antiviral compounds with viral proteins, demonstrating sub-nanomolar KD values and covalent interactions.

2 citations

protein structureexperimental assay

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedAug 28, 2024

Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Dario Akaberi, Monireh Pourghasemi Lati, Janina Krambrich…·Johan Lennerstrand

This paper identifies potent SARS-CoV-2 main protease inhibitors from a DNA-encoded chemical library using affinity-based selection, achieving an IC50 of 30 nM for compound SLL11.

5 citations

virusexperimental assay

𝕏 PostBluesky