Author

Melia D. Matthews

Cornell UniversityORCID 0000-0003-0147-4219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Karl J. LewisiD· 2 shared Nada NaguibiD· 2 shared Ulrich B. WiesneriD· 2 shared Alexander Saffari· 1 shared Katelyn Lunny· 1 shared Lakhi Raju· 1 shared Lanlan Hai· 1 shared Nuzhat Mukul· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Karl J. LewisORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 31, 2026

Intravital Cholesterol Depletion Reduces Membrane Dynamics and Increases Mechanosensitivity in Osteocytes In Vivo

Melia D. Matthews, Katelyn Lunny, Lakhi Raju…·Karl J. Lewis

This study shows that cholesterol depletion in osteocytes reduces membrane dynamics and alters mechanosensitivity, with sex-dependent effects on Ca2+ signaling in response to mechanical loading.

DOI 10.64898/2026.07.21.739862

mouseimaging

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BioengineeringScientific ReportsPeer-reviewedAug 26, 2025

Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo

Melia D. Matthews, Alexander Saffari, Nuzhat Mukul…·Karl J. Lewis

The paper studies endocytosis in osteocytes in vivo, finding sex-specific differences in dynamin-dependent endocytosis and nanoparticle uptake patterns.

1 citation

mouseimaging

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