Author

Tongguang Wang

National Institutes of HealthORCID 0000-0003-0195-5661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Avindra NathiD· 3 shared Joseph P. SteineriD· 2 shared Valerie McDonaldiD· 2 shared Abdel G. ElkahlouniD· 1 shared Adré du PlessisiD· 1 shared Allison R. HorvathiD· 1 shared Anna M. BagnelliD· 1 shared Benjamin D. GastfriendiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Avindra NathORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 23, 2025

A novel frameshift mutation in Phosphoinositide 3-kinase regulatory subunit 1 (PIK3R1) causes immunodeficiency and Amyotrophic Lateral Sclerosis (ALS)

Brice Calco, Colin L. Sweeney, Joseph P. Steiner…·Farinaz Safavi

The paper identifies a novel PIK3R1 frameshift mutation linked to immunodeficiency and ALS, showing haploinsufficiency causes neuronal dysfunction and apoptosis.

DOI 10.1101/2025.05.23.655625

humanscRNA-seq

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NeurosciencebioRxivPreprintMay 20, 2025

3D organoids containing endothelial and neural cells generation by serial inductions of differentiation on human iPSC-derived embryoid bodies

Tongguang Wang, Anna M. Bagnell, Valerie McDonald…·Avindra Nath

This paper develops 3D brain organoids with endothelial and neural cells using sequential differentiation of iPSC-derived embryoid bodies, showing enhanced angiogenesis and SARS-CoV-2 receptor expression.

1 citation

humanscRNA-seq

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Genetic & Genomic MedicinemedRxivPreprintMay 24, 2024

Building a growing genomic data repository for maternal and fetal health through the PING Consortium

Clara M. Abdelmalek, Shriya Singh, Blain Fasil…·Youssef A. Kousa

The PING Consortium builds a genomic data repository to study genetic modifiers of prenatal viral infections' effects on brain development and neurodevelopmental outcomes.

DOI 10.1101/2024.05.24.24307899

humanwhole-exome sequencing

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