Joseph P. Steiner

This study identifies phosphoproteomic dysregulation as a driver of tumor proliferation in Cushing's disease and demonstrates reversibility using an FDA-approved PP2A agonist.

The paper identifies a novel PIK3R1 frameshift mutation linked to immunodeficiency and ALS, showing haploinsufficiency causes neuronal dysfunction and apoptosis.

This paper develops 3D brain organoids with endothelial and neural cells using sequential differentiation of iPSC-derived embryoid bodies, showing enhanced angiogenesis and SARS-CoV-2 receptor expression.