Shaun M. Goodyear

ACCREDIT improves cross-modal image registration by detecting failures and automatically recovering alignments, outperforming existing methods in accuracy and robustness.

This paper introduces a cyclic immunofluorescence platform using photocleavable linkers for direct antibody labeling, enabling more effective cancer phenotyping with reduced specimen damage.

This study evaluates chemical decrosslinking to improve proteome coverage in FFPE tissues, finding that 3,4-diaminobenzoic acid enhances precursor identifications in pancreatic samples.

The paper identifies resistance mechanisms to KRAS-MEK pathway targeting in PDAC by analyzing clinical trial data and multi-omics profiles, showing that KRAS/MYC co-gain correlates with resistance and that co-targeting these genes is synergistic.