Motoshi Hayano

This study examines age-related changes in YAP signaling during skin wound healing in mice, finding altered temporal regulation and selective Ankrd1 elevation in aged wounds.

This study shows that Rif1 overexpression in fission yeast causes mitotic defects and cell death by altering chromatin localization at the nuclear periphery.

This study shows that violet light improves memory and mood in aged mice by activating OPN5-positive retinal ganglion cells and modulating brain regions like the habenula.

The paper shows that DNA double-strand breaks induce epigenomic changes that accelerate the aging clock in mammals.

The paper shows that inducing DNA breaks accelerates aging-related chromatin changes and loss of cell identity in mammals.