Author

Jacek W. Sikora

AbbVie (United States)ORCID 0000-0003-0240-567XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

Andrew W. TrumaniD· 1 shared Bo Zheng· 1 shared Bryan A. KillingeriD· 1 shared Cinzia KlemmiD· 1 shared Claudio A. SotoiD· 1 shared Ehraz AnisiD· 1 shared Jade E. Takakuwa· 1 shared Jake T. KlineiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Andrew W. TrumanORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 7, 2025

Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients

Ehraz Anis, Saima Zameer, Josh Wierenga…·Bryan A. Killinger

The paper examines alpha-synuclein aggregation and molecular changes in appendix tissues from synucleinopathy patients compared to controls.

DOI 10.1101/2025.10.07.680938

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintAug 25, 2021

A novel multifunctional role for Hsp70 in binding post-translational modifications on clients

Nitika Nitika, Bo Zheng, Linhao Ruan…·Andrew W. Truman

This paper uses cross-linking mass spectrometry to characterize Hsp70 interactions in budding yeast, revealing self-association, multi-point client interactions, and novel PTMs critical for client function.

3 citations

yeastproteomics

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