Bo Zheng

Pre-clinical efficacy of a C4BP hexameric IgG Fc fusion protein against Neisseria gonorrhoeae

This paper demonstrates that a hexameric C4BP IgG Fc fusion protein significantly enhances complement-dependent bactericidal activity and reduces gonococcal vaginal colonization in mice.

Structure and dynamics of human disease-complication network

The paper compiles and analyzes the Human Disease-Complication Network to uncover its structure, dynamics, and functional motifs.

A novel multifunctional role for Hsp70 in binding post-translational modifications on clients

This paper uses cross-linking mass spectrometry to characterize Hsp70 interactions in budding yeast, revealing self-association, multi-point client interactions, and novel PTMs critical for client function.

The RNA Structurome in the Asexual Blood Stages of Malaria Pathogen Plasmodium falciparum

This study measures RNA secondary structures in Plasmodium falciparum during asexual development, finding that ~71% of structured RNAs are protein-coding and that structural content correlates with translation efficiency.