Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients
Ehraz Anis, Saima Zameer, Josh Wierenga, Peipei Li, Jacek W. Sikora, Juozas Gordevičius, Meghan Schilthuis, Richard D. LeDuc, Jeffrey H. Kordower, Michelle A. Pinho, Sandra Pritzkow, Claudio A. Soto, Patrik Brundin, Lena Brundin, Bryan A. Killinger
The paper examines alpha-synuclein aggregation and molecular changes in appendix tissues from synucleinopathy patients compared to controls.
bioRxiv · Oct 7, 2025 · PreprintNeuroscience